Education

What is ALA?

Alpha-lipoic acid is an antioxidant that helps the body turn glucose into energy. The body produces it, and each cell contains it. Antioxidants often target “free radicals,” which are dangerous chemical reactions that can injure human cells and impair the body’s ability to fight off diseases. While most antioxidants work only in water, like vitamin C, or fatty tissues, like vitamin E, alpha-lipoic acid is both fat- and water-soluble. 

Benefits of ALA:

• Assist in diabetic peripheral neuropathy symptoms such as pain, burning, itching, tingling, and numbness in the arms and legs.
• Prevents organ dysfunction
• Shown to decrease cell viability and proliferation in breast, ovarian, colorectal, and lung cancer cell lines
• Treats liver disease
• Reduces endothelial dysfunction
• Treat and/or prevent cardiovascular disease
• Accelerates chronic wound healing
• Improve and/or prevent age-related cognitive dysfunction
• Prevent and/or slow down the progression of Alzheimer’s disease
• Reduces inflammation
• Treats chronic diseases associated with oxidative stress
• Lowers blood sugar

Availability:

Alpha-lipoic acid is available through high-dose IV therapy and in supplement form (view our Shop Tab for oral ALA and Specialties Tab for ALA IV Therapy)

Foods that Contain ALA:

• Red meat (beef, pork, lamb)
• Organ meats (liver, kidney)
• Spinach
• Broccoli
• Brussels Sprouts
• Potatoes

Methylene Blue

1. Photodynamic Therapy (PDT):

• Methylene blue acts as a photosensitizer, making cancer cells more vulnerable to light-based treatment. 
• When exposed to light of a specific wavelength, MB generates reactive oxygen species (ROS), which damage and kill cancer cells. 
• MB is a low-cost and safe drug that can be used in PDT, making it a potentially accessible and effective cancer therapy. 
• PDT using MB has shown promise in treating various cancers, including colorectal, skin, pulmonary, esophageal, and cervical cancers. 
• MB can selectively accumulate in cancer cells, further enhancing the effectiveness of PDT. 

2. Metabolic Therapy:

• Some studies suggest that MB can inhibit the growth of cancer cells by targeting their metabolism. 
• MB has been shown to reduce the proliferation of ovarian cancer cells, including those resistant to chemotherapy. 
• Research indicates that MB may induce apoptosis (programmed cell death) in cancer cells, potentially offering a targeted therapeutic approach. 

https://pmc.ncbi.nlm.nih.gov/articles/PMC10568458

Ivermectin

Ivermectin has powerful antitumor effects, including the inhibition of proliferation, metastasis, and angiogenic activity, in a variety of cancer cells. This may be related to the regulation of multiple signaling pathways by ivermectin through PAK1 kinase. On the other hand, ivermectin promotes programmed cancer cell death, including apoptosis, autophagy and pyroptosis. Ivermectin induces apoptosis and autophagy is mutually regulated. Interestingly, ivermectin can also inhibit tumor stem cells and reverse multidrug resistance and exerts the optimal effect when used in combination with other chemotherapy drugs.

https://pmc.ncbi.nlm.nih.gov/articles/PMC7505114

Low Dose Naltrexone

Research Study #1:

This review aims to present current evidence on the potential use of low-dose naltrexone (LDN) in cancer therapy. Low-dose naltrexone exhibits an inhibitory effect on cancer cell proliferation by blocking the opioid growth factor–receptor axis and enhancing the immune response against cancer cells. Data from existing studies indicate that low-dose naltrexone has a high anti-cancer potential, especially as an adjuvant in conventional chemotherapy and immunotherapy schemes.

Naltrexone (NTX) is a non-selective antagonist of opioid receptors, primarily used in the therapy of opioid and alcohol dependence. Low-dose naltrexone (LDN) exhibits antagonistic action against the opioid growth factor receptor (OGFr), whose signaling is associated with the survival, proliferation, and invasion of cancer cells. The mechanism of action of LDN depends on the dose and duration of the OGFr blockade, leading to a compensatory increase in the synthesis of the opioid growth factor (OGF), which has an inhibitory effect on carcinogenesis. Numerous studies on in vitro and in vivo models provide evidence of LDN’s positive impact on inhibiting the OGF–OGFr axis in cancers. LDN’s unique mechanism of action on cancer cells, lack of direct cytotoxic effect, and immunomodulating action form the basis for its use as an adjuvant in chemotherapy and immunotherapy of cancerous lesions.

https://pmc.ncbi.nlm.nih.gov/articles/PMC10968813

Research Study #2:

This review aims to present current evidence on the potential use of low-dose naltrexone (LDN) in cancer therapy. Low-dose naltrexone exhibits an inhibitory effect on cancer cell proliferation by blocking the opioid growth factor–receptor axis and enhancing the immune response against cancer cells. Data from existing studies indicate that low-dose naltrexone has a high anti-cancer potential, especially as an adjuvant in conventional chemotherapy and immunotherapy schemes.

Naltrexone (NTX) is a non-selective antagonist of opioid receptors, primarily used in the therapy of opioid and alcohol dependence. Low-dose naltrexone (LDN) exhibits antagonistic action against the opioid growth factor receptor (OGFr), whose signaling is associated with the survival, proliferation, and invasion of cancer cells. The mechanism of action of LDN depends on the dose and duration of the OGFr blockade, leading to a compensatory increase in the synthesis of the opioid growth factor (OGF), which has an inhibitory effect on carcinogenesis. Numerous studies on in vitro and in vivo models provide evidence of LDN’s positive impact on inhibiting the OGF–OGFr axis in cancers. LDN’s unique mechanism of action on cancer cells, lack of direct cytotoxic effect, and immunomodulating action form the basis for its use as an adjuvant in chemotherapy and immunotherapy of cancerous lesions.

https://pmc.ncbi.nlm.nih.gov/articles/PMC10968813

High Dose Vitamin C + Mistletoe Therapy + Helleborus Therapy

https://riordanclinic.org/what-we-do/integrative-oncology-at-riordan-clinic/?gad_source=1&gbraid=0AAAAA9_xnu_KN1753gjbKp7eGgJCVjV9r&gclid=CjwKCAjw8IfABhBXEiwAxRHlsIDFf_0HMFpcALe02uVtjfZGW6SKa-mRBMliqTfaEqZmPUgRTYlINxoCrGMQAvD_BwE

What is Glutathione?

Glutathione, also known as GSH, is a molecule found naturally in your body. It is produced by the liver and nerve cells in the central nervous system. Glutathione is made up of three amino acids: L-cysteine, glycine, and L-glutamate.

It is an antioxidant, a molecule that helps fight free radicals. Free radicals are unstable molecules that form in response to factors like your diet and the environment. When more free radicals exist than antioxidants, oxidative cell damage occurs. This can lead to inflammation and a variety of health issues ranging from high blood pressure and diabetes to Alzheimer’s disease and more. https://www.peptidesciences.com/blog/what-is-glutathione

Foods with High Levels of Glutathione:

• Turmeric
• Avacado
• Green Asparagus
• Almonds
• Okra
• Broccoli

What have Research Studies Shown?

• Antioxidant activity

• Prevent cancer progression

• Reduce cell damage in liver disease

• Improve insulin sensitivity

• Reduce symptoms of Parkinson’s disease

• Reduce ulcerative colitis damage

• Treating autism spectrum disorders

• Direct chemical neutralization of singlet oxygen, hydroxyl radicals, and superoxide radicals

• Cofactor for several antioxidant enzymes

• Regeneration of vitamins C and E

• Neutralization of free radicals produced by Phase I liver metabolism of chemical toxins

• One of approximately 7 liver Phase II reactions, which conjugate the activated intermediates produced by Phase I to make them water soluble for excretion by the kidneys

• Transportation of mercury out of cells and the brain

• Regulation of cellular proliferation and apoptosis

• Vital to mitochondrial function and maintenance of mitochondrial DNA (mtDNA)

https://www.peptidesciences.com/blog/what-is-glutathione

• Fruits and Vegetables: Colorful fruits and vegetables contain natural antioxidants and polyphenols. These are chemicals in plants that guard against inflammation. Research shows that vitamin K-rich leafy greens like spinach and kale, berries, and yellow and orange fruits and vegetables may be particularly protective.
• Whole Grains: The fiber in oatmeal, brown rice, whole wheat bread, and other whole grains may help with inflammation.
• Beans: They’re high in fiber. Plus they’re loaded with antioxidants and other anti-inflammatory substances.
• Tofu and Tempeh: Soy-based products are high in polyunsaturated fat, fiber, calcium, and vitamins but low in saturated fat. Studies suggest people who eat soy-based foods have lower odds of inflammation-related diseases like heart disease, diabetes, and some cancers.
• Nuts and Legumes: Tree nuts like almonds and walnuts, along with peanuts, are rich in unsaturated fats, along with anti-inflammatory vitamins and minerals. 
• Fish: Fatty fish like salmon, tuna, and sardines are packed with anti-inflammatory omega-3 fatty acids.

• Black Pepper
• Cardamom
• Cinnamon
• Clove
• Cumin
• Curcumin (has the most anti-inflammatory research)
• Fenugreek
• Fennel
• Garlic
• Ginger
• Onion
• Rosemary

• Tea: Green, white, and black teas obtain polyphenols, which are a strong antioxidant. Green and white teas have the MOST anti-inflammatory effects.
• Coffee: Similar to tea, coffee contains antioxidants and caffeine.
• Green Smoothies: Drink your fruits and vegetables in a blended form. You can blend berries along with leafy greens such as spinach or kale with a non-dairy or low-fat milk to get an anti-inflammatory boost.
• Water: Adequate water supply increases hydration and our ability to fight inflammation by flushing out toxins.

Wheatgrass Juice:

• Drink two freshly squeeze ounces per day for an extended time, if not always.
• You can also use the juice or pulp of implants, bathing, poultices, etc.

Benefits of Juicing Wheatgrass:

• High in nutrients and antioxidants
• May reduce cholesterol
• Could help kill cancer cells
• Aid in blood sugar regulation
• Alleviate inflammation
• Promote weight loss

Green Drinks:

• Green drinks are mixtures of freshly squeeze juices, 50% sprouts (pee or sunflower) and 50% vegetable (25% cucumber + 25% celery).
• Drink at least two green drinks per day for the rest of your life.
• Drink on an empty stomach and do not eat for 15-30 minutes afterwards.

Benefits of Green Drinks:

• Improve gut health
• Reduce inflammation
• Strengthen immune system
• Hydrate skin
• Boost energy levels